Articles tagged with: Bioinformatics

Cancer evolution follows natural law - using maths to predict progression

Posted in Publications Published by Marianne Baker 19 January 2016

Cancer evolution follows natural law - using maths to predict progression

Dr Trevor Graham from our Centre for Tumour Biology has co-authored a new study in Nature Genetics, revealing new insights about evolutionary patterns of certain tumours.

This understanding could help us to predict tumour growth for some types of cancer and advance personalised medicine...

Clearing a path for better cancer treatments

Posted in Publications Published by Marianne Baker 15 September 2015

Clearing a path for better cancer treatments

Our researchers have a collaborative study published in Nature Communications on a new computational method to study biological signalling networks in healthy and cancer cells.

The method studies targets and effects of cancer drugs and ultimately could be used to routinely identify the best drug to treat patients...

SEARCHBreast: reducing the need for animal models in breast cancer research

Posted in Publications Published by Marianne Baker 23 July 2015

SEARCHBreast: reducing the need for animal models in breast cancer research

Researchers here at BCI have developed the secure searchable online tissue database called SEARCHBreast in line with the "Replacement, Refinement and Reduction" or 3Rs of animals in research.

More funding has become available to develop tools and techniques that avoid repeating animal experiments and to make the most of the results we already have...

Improving bowel cancer prevention and treatment: new CR-UK grant

Posted in Grants & Awards Published by Marianne Baker 16 July 2015

Improving bowel cancer prevention and treatment: new CR-UK grant

Dr Trevor Graham in our Centre for Tumour Biology will receive a Career Development Award of approximately £1m from Cancer Research UK to study the evolution of human colorectal cancer.

This long-term project aims to help us understand how bowel cancer develops, so that it can be prevented...

BCI PhD student takes the TEDx stage to talk cancer evolution

Posted in Engagement Published by Marianne Baker 01 July 2015

BCI PhD student takes the TEDx stage to talk cancer evolution

Our PhD student William Cross from Dr Trevor Graham's Evolution in Cancer Laboratory gave a talk at the TEDxGoodenoughCollege event in May. 

Entitled "How Cancer Evolves Over Time", you can now watch it in full online...

The Breast Cancer Campaign Tissue Bank: Bioinformatics Portal

Posted in Publications Published by Marianne Baker 09 June 2015

The Breast Cancer Campaign Tissue Bank: Bioinformatics Portal

BCI's Bioinformatics group has worked with Breast Cancer Campaign and the Tissue Bank project to create a bioinformatics tool that allows researchers to get more from samples and the literature...

Barts Charity funds new project to predict cancer risk in patients with inflammatory bowel disease

Posted in Grants & Awards Published by Marianne Baker 31 March 2015

Barts Charity funds new project to predict cancer risk in patients with inflammatory bowel disease

Dr Trevor Graham has been awarded £465,000 by the Barts Charity to lead a project that aims to develop the tools to predict bowel cancer risk in ulcerative colitis patients.

The study, which involves hospitals across London, aims to spare low-risk patients unnecessary surveillance endoscopies and surgery...

Gathering in-depth knowledge of cell signals to help us choose the right cancer drugs – new grants

Posted in Grants & Awards Published by Marianne Baker 04 March 2015

Gathering in-depth knowledge of cell signals to help us choose the right cancer drugs – new grants

Dr Pedro Cutillas in the Centre for Haemato-Oncology has been awarded two new grants from the BBSRC and Barts Charity.

The group will create a database of cell responses to drugs, which will in turn be used to improve cancer treatment by matching these cancer-specific responses to the most suitable drugs...

New method to predict which pancreatic cancers are more aggressive

Posted in Publications Published by Marianne Baker 17 February 2015

New method to predict which pancreatic cancers are more aggressive

Dr Claude Chelala and her Bioinformatics group have tested a new way to classify and recommend treatment for pancreatic cancer patients. The results were published recently in Genome Medicine.

With further work to understand pancreatic cancer biology, the 36-gene signature they have described should provide opportunities to develop new drugs and methods to identify high-risk patients...

Tumour Heterogeneity and the Microenvironment Conference

Posted in Conferences Published by Marianne Baker 12 February 2015

Tumour Heterogeneity and the Microenvironment Conference

The Tumour Microenvironment and Heterogeneity Conference was held in Ohio from 2-6 February 2015 and was co-organised by our Dr Trevor Graham.

The conference brought together cancer geneticists, microenvironment experts and mathematicians to tackle big questions and challenges in cancer research...

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