Articles tagged with: Immunology

Introducing BCI Animations - blood cancers and solid tumours

Posted in General News, Engagement Published by Marianne Baker 13 March 2017

Haemato-Oncology and Tumour Biology

Introducing BCI Animations - blood cancers and solid tumours

BCI has been working with Phospho Biomedical Animations to bring some of our key cancer research topics to life.

Watch these short videos to learn about two of our research Centres' major experimental subjects. Let us know what you think!

Improving transplant therapy through "reverse translation" studies

Posted in Charity, Publications Published by Marianne Baker 01 July 2016

Two new publications made possible by the BCI Charity

Improving transplant therapy through

Two papers have been published by Dr Jeff Davies’ group focusing on the role of immunology in bone marrow transplant, a common and effective treatment for many types of blood cancer.

Both papers are examples of taking a clinical problem into the laboratory to find out why it’s happening and how we might go about fixing it. The second won our Paper of the Month competition in April 2016...

Chemotherapy before surgery could boost ovarian cancer response to immunotherapy

Posted in In the Press, Publications Published by Marianne Baker 15 June 2016

New study published in Clinical Cancer Research by Prof Balkwill

Chemotherapy before surgery could boost ovarian cancer response to immunotherapy

Professor Fran Balkwill has published a study on ovarian cancer responses to treatment, which could mean hope for patients whose cancer has already spread.

The findings suggest that giving chemotherapy before surgery could improve tumour responses to immunotherapy given afterwards, by making the cancer cells more susceptible to immune attack by the immune system...

FDA approves new bladder cancer treatment following BCI-led clinical trial

Posted in General News Published by Marianne Baker 20 May 2016

Tecentriq is the first PD-L1 inhibitor approved by the FDA

FDA approves new bladder cancer treatment following BCI-led clinical trial

Following a groundbreaking trial of a new bladder cancer treatment published in Nature in late 2014 and led by the BCI, the US Food and Drug Administration has now approved the immunotherapy for patients with advanced disease.

This is the first treatment advance for this cancer type in 3 decades and, now it has received first approval, should help many patients for whom existing treatments have not proved effective. European approval will hopefully follow.

Centre for Experimental Cancer Medicine Symposium

Posted in Conferences, Events Published by Marianne Baker 29 October 2015

Centre for Experimental Cancer Medicine Symposium

Recently we held a half-day of talks here at the Institute to highlight the role of our Centre for Experimental Cancer Medicine in setting up and running local, national and international clinical trials.

In memory of Gordon Hamilton Fairley, Barts cancer research Professor

Posted in In the Press Published by Marianne Baker 23 October 2015

Killed 40 years ago today

In memory of Gordon Hamilton Fairley, Barts cancer research Professor

40 years ago today, Professor Gordon Hamilton Fairley was killed by an IRA bomb.

On the anniversary of his death, we celebrate his contributions, and that of so many great cancer researchers who have followed and continue to push the boundaries for patient benefit and for our knowledge of this still-pervasive disease...

Inaugural Greg Wolf Symposium

Posted in Charity, Events, Grants & Awards Published by Marianne Baker 30 September 2015

Inaugural Greg Wolf Symposium

This half-day of talks about blood cancer research honoured the life of Greg Wolf, who was diagnosed with leukaemia in 2002 at the age of 20.

His family set up the Greg Wolf Fund in 2005 in their son’s memory, and over the last decade the organisation has been tirelessly raising funds to support patients and fund blood cancer research...

Tackling ovarian cancer on two fronts

Posted in Grants & Awards Published by Marianne Baker 28 September 2015

Armed with viruses and the immune system

Tackling ovarian cancer on two fronts

Dr Michelle Lockley in our Centre for Molecular Oncology now has a Cancer Research UK Clinician Scientist Fellowship to continue working on oncolytic viruses for ovarian cancer.

High grade serous cancer (HGSC) is the most common subtype of ovarian cancer. Chemotherapy is usually successful at first, but > 70% of patients develop resistance...

Unmasking leukaemia cells: PD-L1 blockade to control blood cancer

Posted in Publications Published by Marianne Baker 14 July 2015

Unmasking leukaemia cells: PD-L1 blockade to control blood cancer

Two new papers from our Centre for Haemato-Oncology in the journal Blood show that boosting the immune system could help control Chronic Lymphocytic Leukaemia (CLL).

The studies focus on two proteins called “Programmed Death Ligand 1” (PD-L1) and Programmed Death 1” (PD-1), found on the surface of tumour and immune cells respectively...

New Bridge to the Future scheme launched thanks to fundraisers for BCI

Posted in Charity, Grants & Awards, Interviews Published by Marianne Baker 01 May 2015

New Bridge to the Future scheme launched thanks to fundraisers for BCI

Thanks to all our supporters' efforts, we have launched the brand new Bridge to the Future scheme to support our Early Career Researchers who are taking the next steps to becoming independent cancer researchers and leaders in their field.

The first recipient of this new award is Dr Eleni Kotsiou in our Centre for Haemato-Oncology...

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