Pancreatic Cancer Research Fund Tissue Bank

The Pancreatic Cancer Research Fund Tissue Bank (PCRFTB) is part of the Barts and The London Hospital Human Tissue Resource Centre. The purpose of the tissue bank is to collect, store and share high quality tissue for translational research into pancreatic cancer.

PCRFTB1

Pancreas Tissue Bank featured by BBC News

The Pancreatic Cancer Research Fund has funded the PCRFTB to enable sample and data collection nationally from pancreatic cancer patients with appropriate controls.

The initial key centres include:

  • Barts Health NHS Trust (London)
  • The Royal Free London NHS Foundation Trust
  • ABM University Health Board, Swansea
  • University Hospitals of Leicester NHS Trust
  • Oxford University Hospitals NHS Foundation Trust
  • University Hospital Southampton NHS Foundation Trust

All of these centres will be co-ordinated by the BCI.

Over 1000 patients and individuals without cancer per year will be recruited. Multiple samples are given by each patient (frozen tissue, pancreatic and biliary juices, paraffin blocks, cells, blood, urine and saliva), collected using a secure, web-based, clinical annotation platform. This bio-repository will generate processed DNA and RNA for analysis, as well as cell lines and derived models, in keeping with the 3Rs principle.

The aim is to expand this tissue bank to further interested centres when SLAs are complete. All tissue based molecular, genomic, proteomic (and other –omics) data will be available in an open source, bioinformatic environment to facilitate early translation of discovered biomarkers and treatment strategies into clinical use by reducing duplication and providing a large case-controlled sample base.

 PCRFTB Team

Role

Prof Hemant Kocher Co-Lead
Ms Maggie Blanks CEO, PCRF
Co-Lead
Prof Claude Chelala Bioinformatics & Data Governance
Ms Amina Saad Tissue Collection Officer
TBA Tissue Bank Co-Ordinator
Mr Abu Dayem Ullah Database Manager
Mr Jacek Marzec Bioinformatician

URL https://www.thepancreastissuebank.org/


The Barts Pancreas Tissue Bank

This is the local tissue bank counterpart to the PCRF Tissue Bank. It holds the Barts Health NHS Trust patient samples gathered by researchers from Barts Cancer Institute.

Barts Pancreas Tissue Bank team

Role

Prof Hemant Kocher Co-Lead
Prof Claude Chelala Bioinformatics & Data Governance
Dr Vickna Balarajah Clinical Research Fellows
Dr Abhirup Banerjee

Further information: https://www.bartspancreastissuebank.org.uk

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