Ms Hemalvi Patani

Human naive pluripotency – a model system for understanding the mechanisms of aberrant DNA methylation in cancer". In this project we explore the recently identified conditions to induce the human naïve pluripotency and analyse the observed parallels with cancer cells and in particular cancer stem cells. These cells adopt epigenetic patterns that are reminiscent of those seen in cancer and makes the system therefore ideal to understand the molecular mechanism of this process.

Supervisor:

Dr Gabriella Ficz
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