Category: Interviews

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Combining medicine with blood cancer research

3rd September 2021

This Blood Cancer Awareness Month, we spoke with Dr John Riches, Clinical Senior Lecturer at Barts Cancer Institute (BCI), Queen Mary University of London. Dr Riches is a clinician scientist who splits his time between BCI where he leads a group researching blood cancer in our Centre for Haemato-Oncology and directs the MSc Cancer & Clinical Oncology Programme, and St Bartholemew’s Hospital where he treats blood cancer patients.

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Dissecting complex biological pathways with machine learning

19th July 2021

We spoke with Group Leader Dr Jun Wang and Postdoctoral Researcher Dr Anthony Anene from Barts Cancer Institute’s Centre for Cancer Genomics & Computational Biology about their most recent publication. Published in Patterns, the paper describes the development of a machine-learning tool called ACSNI that can be used to predict tissue-specific pathway components from large biological datasets.

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Ovarian Cancer Perspectives: Q&A with Dr Michelle Lockley

18th March 2021

In recognition of Ovarian Cancer Awareness Month, we spoke with Dr Michelle Lockley, Group Leader and clinical researcher in BCI’s Centre for Cancer Cell and Molecular Biology. Dr Lockley’s research group focuses on improving treatments for women with ovarian cancer, particularly for those whose tumours are resistant to chemotherapy.

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Cancer cell communications

12th March 2021

We spoke with Dr Susana Godinho, Group Leader in Barts Cancer Institute’s Centre for Cancer Cell and Molecular Biology, to find out about her recent paper published in Current Biology. Dr Godinho and her team set out to identify why cancer cells carrying extra centrosomes exhibit increased release of communications packages known as small extracellular vesicles.

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Chromosomal instability in ovarian cancer

26th November 2020

We spoke with Dr Sarah McClelland and senior postdoctoral researcher in her group, Dr Nadeem Shaikh, about the team’s most recent paper, published in Cancer Research, which set out to explore the mechanisms of chromosomal instability in high-grade serous ovarian carcinoma – the most common type of ovarian cancer. The study sheds light on how these mechanisms may be able to be targeted to overcome treatment resistance in this cancer type.

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Protein powerhouses – Q&A with Dr Mardakheh

9th November 2020

We spoke with Dr Faraz Mardakheh from Barts Cancer Institute’s Centre for Cancer Cell and Molecular Biology about his most recent research paper, published today in Developmental Cell. The study sheds lights on how invasive cancer cells increase their protein-making capacity in order to boost their growth and invasive capabilities, and identifies a key player involved in this process, which may represent a target for therapeutic interventions.

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