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Immunotherapy for advanced bladder cancer

18th September 2020

An immunotherapy drug called ‘avelumab’ has been shown to significantly improve survival in patients with the most common type of bladder cancer, according to results from a phase III clinical trial led by Professor Tom Powles.

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Investigating new treatment options for mesothelioma

16th September 2020

Results from a phase I clinical trial led by Professor Peter Szlosarek were recently published in JTO Clinical and Research Reports. The trial was investigating the safety and efficacy of a new drug combination for the treatment of mesothelioma. We spoke to Professor Szlosarek to find out more about the trial, and how the drug combination may be able to help patients with mesothelioma.

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Immune ‘cloaking’ in cancer cells

14th September 2020

Researchers have created a mathematical model that can determine the impact of the immune system on tumour evolution. The information gained from using this model may be able to be used to predict whether immunotherapy is likely to be effective for a patient’s cancer, helping to guide treatment decisions.

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Biological clues in tissues surrounding breast tumours

9th September 2020

A new study has identified molecular characteristics in ‘normal-looking’ tissues surrounding breast tumours that may indicate whether breast cancer is likely to return following surgical removal of the tumour.

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Using AI to study tumour evolution

2nd September 2020

Researchers have developed a computation model that can reconstruct the evolutionary history of cancer. By unravelling the genetic complexity of a tumour, the tool can be used to better understand how the cancer has developed and may help to guide treatment strategies in the future.

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Proposed new surgery protocol for ovarian cancer

17th August 2020

For women at high risk of ovarian cancer, standard preventive practice is to offer removal of both the fallopian tubes and ovaries, but the surgery induces menopause in women who have not yet reached this stage of life. A proposed alternative two step surgical protocol, which delays the induced menopause caused by the removal of the ovaries, is highly acceptable to this premenopausal group of women.

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