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Eliminating cancer stem cells
25th April 2019
Research published today in Cell Stem Cell has discovered a protein which drives an aggressive form of blood cancer, acute myeloid leukaemia (AML). Inactivation of this protein selectively compromises leukaemic cells while promoting normal blood cell functions.
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Therapy for high-grade glioma
2nd April 2019
A phase I clinical trial that set out to assess the safety of a new combination therapy for a type of aggressive brain tumour has found the treatment to be well tolerated in patients. The trial used a treatment combination of ADI-PEG20, pemetrexed and cisplatin, which showed encouraging efficacy in patients with recurrent high-grade gliomas (HGGs), a disease for which little progress has been made over the last few decades.
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Flying in the face of cancer
27th February 2019
Using flies to reveal mechanisms of cancer development- Q&A with Dr Ribeiro Dr Paulo Ribeiro and his team. From left to right: Paulo Ribeiro, Lauren Dawson, Alberto Rizzo and Damien […]
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Tackling tumour scar tissue could be key to treating pancreatic cancer
11th February 2019
The first study in the world to take a detailed look at scar tissue in human pancreatic cancer has revealed a range of different scar tissue types that could help clinicians predict which patients will respond best to particular treatments.
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Immune cells found as accomplices in melanoma spread
31st January 2019
A new study published today in Cell has revealed that aggressive melanoma cells are able to manipulate the immune system to their advantage. As a result, immune cells that are supposed to recognise and destroy cancer cells actually behave differently and support the growth and spread of the tumour.
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‘The neighbouring effect’: Centrosomal abnormalities drive invasion of surrounding cells
19th November 2018
Centrosomal amplification, a particular change that occurs within some cancer cells, has been shown to drive the invasion of neighbouring cancer cells.
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