We conduct research into the prevention of cancer with particular focus on preventive therapy and screening. We are involved in clinical trials and epidemiology and as such our work is essentially collaborative. Activities encompass prevention studies, screening studies, treatment comparisons, prognostic factors and biomarkers for survival, and aetiological studies of risk factors and biomarkers for developing cancer. The analysis of data from our projects often requires the development of new mathematical and statistic techniques, and we have an active interest in the development of new methodology.