Tag: Cells
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How cancer cells shapeshift to spread through the body
23rd August 2023
Researchers show how cancer cells rearrange their inner workings to squeeze between obstacles
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BCI researcher receives prestigious MRC grant to investigate how HPV infection develops into cancer
27th May 2022
Dr Sarah McClelland from BCI is part of a collaborative project that has secured £1.2 million in funding from the Medical Research Council to investigate the mechanisms leading to cancer development in cells infected with human papillomavirus.
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Cancer cell communications
12th March 2021
We spoke with Dr Susana Godinho, Group Leader in Barts Cancer Institute’s Centre for Cancer Cell and Molecular Biology, to find out about her recent paper published in Current Biology. Dr Godinho and her team set out to identify why cancer cells carrying extra centrosomes exhibit increased release of communications packages known as small extracellular vesicles.
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Chromosomal instability in ovarian cancer
26th November 2020
We spoke with Dr Sarah McClelland and senior postdoctoral researcher in her group, Dr Nadeem Shaikh, about the team’s most recent paper, published in Cancer Research, which set out to explore the mechanisms of chromosomal instability in high-grade serous ovarian carcinoma – the most common type of ovarian cancer. The study sheds light on how these mechanisms may be able to be targeted to overcome treatment resistance in this cancer type.
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Novel insights into graft-versus-host disease
13th October 2020
Research led by Barts Cancer Institute, Queen Mary University of London, has identified a subset of immune cells involved in site-specific tissue damage in cancer patients who have developed harmful graft-versus-host disease after stem cell transplantation. The insights gained from the study may help to define new targets for more selective approaches to prevent or treat this condition in patients who have received a stem cell transplant.
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Unravelling the circuitry that controls cancer growth and spread
23rd June 2020
Research reveals novel insights into the molecular circuitry controlling cancer cell growth and spread. The findings highlight new pathways involved in these key processes of cancer progression that may represent targets for therapies.
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